Jiang Bian, PhD

Data is powerful, but unlocking its true potential through data science and AI to drive real-world impact is where the real magic happens.

Initiatives

Chief Data Scientist, Regenstrief Institute
Chief Data Scientist, IU Health
Walther and Regenstrief Endowed Chair in Cancer Informatics, IU Melvin and Bren Simon Comprehensive Cancer Center and Regenstrief Institute
Chief Research Information Officer, IU Melvin and Bren Simon Comprehensive Cancer Center
Associate Dean for Data Science, IU School of Medicine
Regenstrief Deputy Director, Indiana Clinical and Translational Sciences Institute (CTSI)
Professor and Vice Chair for Translational Informatics, Department of Biostatistics and Health Data Science, IU School of Medicine
Adjunct Professor of Biomedical Engineering and Informatics, Department of Biomedical Engineering and Informatics, Luddy School of Informatics, Computing and Engineering at IU Indianapolis

Dr. Bian specializes in biomedical informatics and health data science — interdisciplinary fields focused on leveraging data, information and knowledge to drive scientific discovery, problem-solving and decision-making — all aimed at improving human health. He has a diverse background in data harmonization and integration, AI/machine learning, causal AI, natural language processing, ontology development and evaluation and software engineering. Dr. Bian brings extensive experience in developing real-world data infrastructure, informatics tools and systems, as well as applying advanced AI and data science methods to analyze and interpret multimodal clinical and biomedical data. His work is unified by a focus on harnessing heterogeneous data and knowledge resources and translating them into actionable applications that enhance human health.

Dr. Bian previously served as the Chief Data Scientist and Chief Research Information Officer for University of Florida Health, as well as the Chief Data Scientist for the OneFlorida+ Clinical Research Consortium, among other notable roles.

Featured Projects

ACCELERATE-BASSO: Coordinating Center for Accelerating Behavioral and Social Science through Ontology

NIH/NIA 1 U24AG088019-01

09/01/2024 – 08/31/2029

Role: Principal Investigator (Contact)

Standarizing and Harmonizing Behavioral and Social Science Research Factors in Alzheimer’s Disease through Ontology-Based Approaches

NIH/NIA 1 U01AG088076-01

09/01/2024 – 08/31/2029

Role: Principal Investigator (MPI)

Semantics Standards and Tools for Spatial and Contextual Exposome Data

NIH/NIEHS 1 R24ES036131-01

06/25/2024 – 05/31/2029

Role: Principal Investigator (Contact)

iSMART: intelligent Social risk Management in AD/ADRD paTients

NIH/NIA 1 R01AG089445-01

08/15/2024 – 04/30/2029

Role: Principal Investigator (MPI)

An end-to-end informatics framework to study Multiple Chronic Conditions (MCC)'s impact on Alzheimer's disease using harmonized electronic health records

NIH/NIA 1 R01AG083039-01

09/01/2023 – 05/31/2026

Role: Principal Investigator (MPI)

Post-Acute Sequelae of SARS-CoV-2 Infection and Subsequent Disease Progression in Individuals with AD/ADRD: Influence of the Social and Environmental Determinants of Health

NIH/NIA 1 RF1AG084178-01

09/01/2023 – 06/30/2026

Role: Principal Investigator (MPI)

ACTS (AD Clinical Trial Simulation): Developing Advanced Informatics Approaches for an Alzheimer's Disease Clinical Trial Simulation System

NIH/NIA 1 R01AG084236-01

09/01/2023 – 05/31/2028

Role: Principal Investigator (MPI)

Artificial Intelligence and Counterfactually Actionable Responses to End HIV (AI-CARE-HIV)

NIH/NIAID 1 R01AI172875-01

04/25/2023 – 03/31/2028

Role: Principal Investigator (MPI)

AI-ADRD: Accelerating interventions of AD/ADRD via Machine learning methods

NIH/NIA 1 RF1AG077820-01A1

05/01/2023 – 04/31/2028

Role: Principal Investigator (MPI)

Eligibility criteria design for Alzheimer’s trials with real-world data and explainable AI

NIH/NIA 1 R01AG080991-01

02/01/2023 – 11/30/2027

Role: Principal Investigator (MPI)

Disparities of Alzheimer's disease progression in sexual and gender minorities

NIH/NIA 1 R01AG080624-01

02/15/2023 – 01/31/2028

Role: Principal Investigator (Contact)

PANDA-MSD: Predictive Analytics via Networked Distributed Algorithms for Multi-System Diseases

NIH/NCATS 1 U01TR003709-01A1

07/01/2022 – 06/30/2026

Role: Principal Investigator (MPI)

Computational Drug Repurposing for AD/ADRD with Integrative Analysis of Real World Data and Biomedical Knowledge

NIH/NIA 1 R01AG076234-01

03/01/2022 – 02/28/2027

Role: Principal Investigator (MPI)

Using Real-world Data to Assess the Burden of Diabetes in Children and Adolescents in Florida

CDC 1 U18 DP006512-01

09/30/2020 – 09/29/2025

Role: Principal Investigator (Contact PI)

Highlighted Publications

Oct 5, 2024

A fair individualized polysocial risk score for identifying increased social risk in type 2 diabetes

Publication: Nature Communications

doi: 10.1038/s41467-024-52960-9

Authors: Huang Y, Guo J, Donahoo WT, Lee YA, Fan Z, Lu Y, Chen WH, Tang H, Bilello L, Saguil AA, Rosenberg E, Shenkman EA, Bian J

Dec 26, 2022

A large language model for electronic health records

Publication: NPJ Digital Medicine

doi: 10.1038/s41746-022-00742-2

Authors: Yang X, Chen A, PourNejatian N, Shin HC, Smith KE, Parisien C, Compas C, Martin C, Costa AB, Flores MG, Zhang Y, Magoc T, Harle CA, Lipori G, Mitchell DA, Hogan WR, Shenkman EA, Bian J, Wu Y

Dec 11, 2023

High-throughput target trial emulation for Alzheimer's disease drug repurposing with real-world data

Publication: Nature Communications

doi: 10.1038/s41467-023-43929-1

Authors: Zang C, Zhang H, Xu J, Zhang H, Fouladvand S, Havaldar S, Cheng F, Chen K, Chen Y, Glicksberg BS, Chen J, Bian J, Wang F

July 13, 2020

Causal inference and counterfactual prediction in machine learning for actionable healthcare

Publication: Nature Machine Intelligence

doi: 10.1038/s42256-020-0197-y

Authors: Prosperi M, Guo Y, Sperrin M, Koopman JS, Min JS, He X, Rich S, Wang M, Buchan IE, Bian J

July 16, 2024

Glucagon-Like Peptide-1 Receptor Agonists and Risk for Suicidal Ideation and Behaviors in U.S. Older Adults With Type 2 Diabetes : A Target Trial Emulation Study

Publication: Annals of Internal Medicine

doi: 10.7326/M24-0329

Authors: Tang H, Lu Y, Donahoo WT, Shao H, Shi L, Fonseca VA, Guo Y, Bian J, Guo J

July 1, 2020

Explainable artificial intelligence models using real-world electronic health record data: a systematic scoping review

Publication: Journal of the American Medical Informatics Association

doi: 10.1093/jamia/ocaa053

Authors: Payrovnaziri SN, Chen Z, Rengifo-Moreno P, Miller T, Bian J, Chen JH, Liu X, He Z

Dec 9, 2020

Assessing the Practice of Data Quality Evaluation in a National Clinical Data Research Network through a Systematic Scoping Review in the era of Real-world Data

Publication: Journal of the American Medical Informatics Association

doi: 10.1093/jamia/ocaa245

Authors: Bian J, Lyu T, Loiacono A, Mendoza-Viramontes T, Lipori G, Guo Y, Wu Y, Prosperi M, George TJ, Harle CA, Shenkman EA, Hogan WR

Apr 1, 2018

Assessing the Practice of Ontology Evaluation for Biomedical Ontologies in BioPortal: Gaps and Opportunities

Publication: Journal of Biomedical Informatics

doi: 10.1016/j.jbi.2018.02.010

Authors: Amith MF, He Z, Bian J, Lossio-Ventura JA (p), Tao C

Feb 23, 2023

Early prediction of Alzheimer's disease and related dementias using real-world electronic health records

Publication: Alzheimer's & Dementia

doi: 10.1002/alz.12967

Authors: Li Q, Yang X, Xu J, Guo Y, He X, Hu H, Lyu T, Marra D, Miller A, Smith G, DeKosky S, Boyce RD, Schliep K, Shenkman E, Maraganore D, Wu Y, Bian J

Mar 5, 2024

A scoping review of fair machine learning techniques when using real-world data

Publication: Journal of Biomedical Informatics

doi: 10.1016/j.jbi.2024.104622

Authors: Huang Y, Guo J, Chen WH, Lin HY, Tang H, Wang F, Xu H, Bian J

Oct 19, 2021

The OneFlorida Data Trust: a centralized, translational research data infrastructure of statewide scope

Publication: Journal of the American Medical Informatics Association

doi: 10.1093/jamia/ocab221

Authors: Hogan WR, Shenkman EA, Robinson T, Carasquillo O, Robinson PS, Essner RZ, Bian J, Lipori G, Harle C, Magoc T, Manini L, Mendoza T, White S, Loiacono A, Hall J, Nelson D

In The News

Influence

Featured Fellowship

People

VideoDr. Johns: Fear of breast cancer recurrence can have an impact on coping

NewsFear of breast cancer recurrence: Impact and coping with being in a dark place

NewsIdentifying ED patients likely to have health-related social needs

VideoDr. Sachs: IN-PEACE study halved ED visits, hospitalizations for dementia patients and their caregivers

NewsJAMA study integrates palliative and dementia care for patients and caregivers

Fear of breast cancer recurrence: Impact and...

Jiang Bian, PhD

Featured Projects

Highlighted Publications