Influence
April 18, 2022

Research from Regenstrief gastroenterologist makes impact; article recognized by professional journal as 1 of most widely cited for 2020-2021

Regenstrief Institute Research Scientist Thomas Imperiale, M.D., is being recognized by the American Association for Cancer Research for an impactful paper. His article Specificity of the Multi-Target Stool DNA Test for Colorectal Cancer Screening in Average-Risk 45-49 Year-Olds: A Cross-Sectional Study” was one of the most highly cited papers in the Journal of Cancer Prevention Research during 2020 and 2021.  

The study examined the performance of multitarget stool DNA tests in individuals aged 45 to 49 at average risk for colon cancer. Results indicated that the tests have high specificity and support their use as a noninvasive option for colorectal cancer screening. This article provided a foundation for numerous other scientists to advance research in this area.  

Dr. Imperiale focuses much of his research on screening and surveillance for colorectal cancer, including tailoring each for individual patient risk. He recently worked with a research team to develop and test a new tool to predict personal risk for advanced precancerous polyps and colon cancer.  

The American Association for Cancer Research journals highlighted Dr. Imperiale’s paper during the organization’s annual conference in April 2022.  

In addition to his role as a research scientist at Regenstrief Institute, Dr. Imperiale is a core investigator for the U.S. Department of Veterans Affairs Health Services Research and Development Center for Health Information and Communication, Richard L. Roudebush VA Medical Center. He is the Lawrence Lumeng Professor of Gastroenterology and Hepatology at Indiana University School of Medicine as well.   

Related News

Regenstrief researcher honored by awards from Indiana University and Ball State University

Regenstrief Institute Research Scientist William Tierney, M.D., renowned for his groundbreaking work in health informatics, population health and global

Thomas Imperiale

Two studies explore impact of pandemic on colorectal cancer screening and diagnosis

Temporary disruption to screening tests but minimal impact on diagnostic colonoscopies INDIANAPOLIS – Two recent studies by researchers from

word cloud graphic of LOINC terminology

Nearly 700 registrants represent 57 countries and production release of LOINC® Ontology at spring webinar

Regenstrief Institute’s Health Data Standards (HDS) team, in collaboration with SNOMED International, hosted 700 registrants representing 57 countries at