Influence
October 7, 2020

Evaluating the link between medications and dementia: Regenstrief researcher provides consultation

Regenstrief Institute research scientist Noll Campbell, PharmD, M.S., recently contributed to a study that made national headlines and provided more evidence that anticholinergic medications are linked to cognitive decline.

The results from the study, led by researchers at the University of California San Diego School of Medicine, were published in Neurology. The authors concluded that anticholinergics are associated with an increased risk of cognitive decline regardless of the presence of genetic or biomarker risk factors for Alzheimer’s disease.

Dr. Campbell consulted on the study, providing perspective on the data based on similar studies he has been involved with at Regenstrief and Indiana University School of Medicine.  He is listed as an author on the paper.

The past research conducted by Dr. Campbell and his colleagues also provides evidence establishing a link between the common type of medication and cognitive decline. He is now leading a clinical trial to determine if deprescribing anticholinergics improves cognition, which could in turn delay or prevent dementia.

In addition to his role as a research scientist at Regenstrief Institute, Dr. Campbell is an assistant professor of pharmacy practice at the Purdue University College of Pharmacy.

Related News

(L to R): Dan Clark, PhD, and Briana Sprague, PhD

Brain training and healthy snacks show promise for older adults with less education

Findings highlight the importance of including underserved populations in dementia prevention research Researchers at the Indiana University School of

Creating User Personas to Represent the Needs of Dementia Caregivers Who Support Medication Management at Home: Persona Development and Qualitative Study

Regenstrief Institute authors: Noll Campbell, PharmD, M.S.; Malaz Boustani, M.D., MPH Understand the strategies and unmet needs of caregivers

Jiang Bian, PhD

GLP-1 RA Use and Survival Among Older Adults With Cancer and Type 2 Diabetes

Published in the JAMA Network Open. Here is a link to the article. Regenstrief Institute authors: Jiang Bian, PhD